Antiviral: Benefits of Manuka honey for colds & flu

Manuka honey for colds has been used for centuries as a natural way to support the body during seasonal illness. Sourced from the nectar of the Leptospermum plant native to Australia and New Zealand, Manuka honey is valued for its unique bioactive properties.

Medical-grade Manuka honey is widely studied for its role in supporting immune health, soothing sore throats, and helping manage symptoms of upper respiratory tract infections. These benefits are supported by a growing body of peer-reviewed research.

A key marker of Manuka honey quality is Methylglyoxal (MGO) - the compound responsible for its strength and potency. The higher the MGO rating, the more concentrated the honey, and typically, the greater its value and application for targeted wellness support.

What makes Manuka honey different?

Manuka honey stands apart from other honeys due to its naturally occurring MGO content. This compound forms from dihydroxyacetone (DHA), which is uniquely present in the nectar of the Leptospermum plant native to Australia and New Zealand. During the natural maturation process of honey, DHA converts into MGO, increasing the honey’s bioactive strength over time.

This natural transformation is what gives Manuka honey its measurable and standardised potency. Unlike conventional honey, where activity can vary widely and is difficult to quantify, MGO provides a clear and scientifically recognised marker of strength and concentration.

The result is a honey with consistent, measurable bioactivity that can be aligned to specific wellness uses. Lower MGO grades are typically suited to everyday wellbeing, while higher MGO concentrations are increasingly valued for targeted support, including during cold and flu season.

At Biosota, this process is carefully respected and preserved. Our Manuka honey is cold-extracted and never heat-treated, helping maintain the integrity of these naturally occurring compounds. Each batch is independently lab-tested in accredited laboratories to verify its MGO rating, ensuring consistency in purity, quality, and strength from hive to jar.

Manuka honey for colds: What the research shows

Colds and flu are most often caused by viruses, which means antibiotics are not suitable for treatment. Instead, the focus typically shifts to supportive care that helps ease symptoms while the body recovers. Manuka honey for colds and flu can play a complementary role in this approach. 

A study published in Archives of Medical Research found that honey, and particularly Manuka honey, demonstrated strong inhibitory activity against the influenza virus in laboratory conditions (1). Researchers found that Manuka honey inhibited influenza virus replication, and that combining it with known antiviral drugs produced a synergistic effect, markedly strengthening the body's defence response.

A follow-up study found that MGO demonstrated strong inhibitory activity against influenza viruses across multiple strains. The research also showed that MGO enhanced the effectiveness of antiviral medications, including against drug-resistant strains, highlighting its potential role as a complementary support in influenza management (2).

Key finding:

In laboratory research, Manuka honey was shown to directly inactivate the influenza virus, with even stronger effects observed when used alongside conventional antiviral medications.

Manuka honey benefits for viral infections

Research has highlighted the antiviral potential of Manuka honey, particularly in relation to common respiratory viruses such as influenza (1).

In addition to these direct antiviral properties, Manuka honey may support the body’s natural immune response, helping to manage the severity of symptoms associated with colds and flu. This combination of functional activity and immune support is what underpins its longstanding use in both traditional remedies and modern wellness routines.

While there was increased interest during the COVID-19 period in how natural products like Manuka honey may support respiratory health, research in this area remains limited. Today, the focus has shifted back to its more established role in supporting the body during common viral illnesses, particularly colds and influenza.

As with all natural health approaches, Manuka honey is best used as a complementary support alongside appropriate medical care.

Manuka Honey Benefits for Sore Throats

A sore throat is one of the most common and uncomfortable symptoms during a cold. In most cases, it is caused by a viral infection, although more severe cases may involve bacterial strains such as Streptococcus. Conventional treatments such as lozenges can offer temporary relief, while pain relief medications or antibiotics may be introduced when clinically required.

Manuka honey offers a natural, evidence-informed complement to this approach, supported by its unique MGO-driven bioactive profile. This measurable potency is what underpins its relevance for targeted seasonal support, particularly when selecting higher MGO grades.

From a practical perspective, Manuka honey supports sore throat relief in two ways. Its thick, viscous texture helps coat and soothe irritated throat tissue, providing immediate physical comfort. At the same time, its bioactive compounds work alongside the body’s natural immune response, helping to manage symptoms more effectively.

This dual benefit is supported by clinical research. Studies involving children with upper respiratory tract infections found that honey reduced cough frequency and severity more effectively than some conventional treatments, while also improving sleep quality (3).

With growing global awareness around antibiotic resistance, high-grade Manuka honey is gaining attention as a natural addition to seasonal care routines. When selected at appropriate MGO levels, it delivers soothing support, grounded in both traditional use and scientific research.

Manuka Honey Benefits for Upper Respiratory Tract Infections

Manuka honey offers a natural, supportive approach to managing upper respiratory tract infections (URTIs), including conditions such as sinusitis and bronchitis. These infections can be persistent and uncomfortable, with symptoms like congestion, coughing, and throat irritation often lingering despite conventional care.

Research highlights the potential role of Manuka honey in this space. Some studies suggest it may help disrupt biofilms - protective layers formed by certain bacteria such as Staphylococcus - which can make infections more difficult to manage.

A systematic review and meta-analysis published in BMJ Evidence-Based Medicine analysed 14 studies and found that honey was superior to usual care in improving symptoms of upper respiratory tract infections. This included reductions in overall symptom severity, as well as improvements in cough frequency and intensity (4).

While painkillers and decongestants may offer temporary relief, these findings position Manuka honey as a valuable complementary option - one that works alongside standard care to support the body’s natural recovery process.

Benefits of Manuka Honey for Bacterial Coughs

Manuka honey is widely recognised as a natural option for cough relief, particularly in children. The American Academy of Pediatrics recommends honey as a supportive approach for managing cough symptoms in children over 12 months of age.

Clinical research further supports this use. In a 2010 study involving 139 children with upper respiratory tract infections, participants received either a single dose of honey, a common cough suppressant (dextromethorphan or diphenhydramine), or a placebo. The results showed that honey was more effective at reducing both the frequency and severity of cough. Parents also reported improved sleep quality compared to children who received conventional medications (5).

For children over the age of one, Manuka honey may offer a gentle, natural way to ease cough symptoms and support more restful sleep during illness. As with all honey, it should not be given to infants under 12 months or to individuals with known allergies to honey or bee products.

Medicinal Manuka Honey - MGO Grades Explained

Premium medicinal Manuka honey is defined as high-grade honey that is independently tested for its curative compounds, including antioxidants, bioflavonoids, and immune-supporting enzymes.

Medicinal-grade Manuka honey presents higher levels of MGO compared to table-grade honey and is naturally bioactive with antimicrobial, antiseptic, and anti-inflammatory properties that support holistic wellbeing.

Common uses of Manuka honey include:

• Cold and flu symptom support

• Sore throat and cough relief

• Immunity support

• Upper respiratory tract infection management

• Oral care and gut health

• Wound and skin support

• General wellbeing

The higher the MGO number, the greater the bioactive potency. Here is a general guide to MGO grades and their typical applications:

The MGO levels of Biosota's high-strength medicinal Manuka honey ranges are regularly tested and verified as authentic by independent accredited laboratories in Australia.

How to Use Medicinal Manuka Honey for Colds and Flu

Keep a jar of medicinal-grade Manuka honey in the medicine cabinet throughout winter and flu season. Aim to use honey in the mid-to-high MGO range. The higher the number, the greater the bioactive potency.

Using Manuka Honey for Colds and Flu

Oral use of high-grade honey may provide relief for nasal and chest congestion or help prevent symptoms from worsening.

• Enjoy as-is, straight from the spoon

• Make warm honey tea with lemon, ginger, or immune-supporting herbs and spices

• Avoid overheating -- high temperatures can destroy essential enzymes, including MGO

Recommended range: MGO 260+ to 880+

For Bacterial Coughs

Start on a slightly higher dose at the peak of the cold or infection: one to two teaspoons twice daily, reducing to one teaspoon per day as symptoms improve.

For Sore Throats

For targeted relief, take a spoonful of Manuka honey directly, allowing it to slowly coat the throat. This helps provide immediate soothing comfort to irritated tissue.

Alternatively, dissolve a spoonful in warm water with a squeeze of lemon to create a gentle, soothing drink. Allow it to cool slightly before sipping or gargling. Repeat once or twice daily as needed.

For Congestion or Sinus Infection

Warm steam inhalation and saline nasal rinses can help relieve congestion and support sinus comfort. While some research has explored the use of Manuka honey in nasal irrigation for chronic sinus conditions, evidence is still evolving.

For most people, Manuka honey is best used orally, where its soothing properties and bioactive compounds can support throat comfort and overall wellbeing during cold and flu season.

* Medicinal Manuka honey usage and dosage suggestions are based on our direct experience, feedback from customers, and the latest published scientific research. Dosage and individual results may vary. Please consult your healthcare provider before beginning any treatment and if symptoms persist.

Frequently Asked Questions

Can Manuka honey help with colds?

Manuka honey has been studied for its antimicrobial and immune-supporting properties. Research published in BMJ Evidence-Based Medicine (2021) found that honey was superior to usual care for relieving upper respiratory tract infection symptoms, including cough frequency and severity. It is best used as a complementary support alongside your existing healthcare plan.

Is Manuka honey antiviral?

Laboratory research has demonstrated that Manuka honey possesses antiviral properties. A study by Watanabe et al. (2014) found that Manuka honey inhibited influenza virus replication in vitro and showed virucidal activity. The high MGO content of Manuka honey is considered a key contributor to these properties, though further clinical research is ongoing.

What MGO level is best for colds and flu? 

For cold and flu support, we recommend Manuka honey in the MGO 260+ to 880+ range. The higher the MGO number, the greater the bioactive potency of the honey.

How much Manuka honey should I take for a cold?

A general starting point is one to two teaspoons twice daily during the peak of symptoms, reducing to one teaspoon per day as you improve. Always consult your healthcare provider for personalised advice.

Can children take Manuka honey for coughs? 

Honey is recommended by the American Academy of Pediatrics for cough relief in children. However, honey should never be given to children under the age of 1, and anyone with a known allergy to honey or bee products should avoid it.

Find Your Ideal Manuka Honey Strength This Cold and Flu Season

At Biosota Organics, our passion lies in the natural healing power of Manuka honey. Our premium Australian Manuka honey is sourced from native Leptospermum species growing in remote bushland and pristine coastal regions of Queensland and New South Wales - cultivated by nature, and verified by science.

Explore our medicinal-grade Manuka honey range and find the right MGO strength for your needs this cold and flu season.

References

1. Watanabe K, Rahmasari R, Matsunaga A, Haruyama T, Kobayashi N. Anti-influenza viral effects of honey in vitro: potent high activity of manuka honey. Archives of Medical Research. 2014;45(5):359–365. https://pubmed.ncbi.nlm.nih.gov/24880005/

2. Watanabe, K., Charyasriwong, S., Rahmasari, R., Matsunaga, A., Haruyama, T., Kobayashi, N., In vitro evaluation of synergistic inhibitory effects of neuraminidase inhibitors and methylglyoxal against influenza virus infection, 2014, Archives of Medical Research, 45(8), 595–601.
   Link: https://pubmed.ncbi.nlm.nih.gov/25523147/

3. Goldman, R.D., Honey for treatment of cough in children, 2014, Canadian Family Physician, 60(12), 1107–1110.
   Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC4264806/

4. Abuelgasim H, Albury C, Lee J. Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis. BMJ Evidence-Based Medicine. 2021;26(2):57–64. https://pubmed.ncbi.nlm.nih.gov/32817011/

5. Paul, I.M., Beiler, J., McMonagle, A., Shaffer, M.L., Duda, L., Berlin, C.M., Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents, 2007, Archives of Pediatrics & Adolescent Medicine, 161(12), 1140–1146.
   Link: https://pubmed.ncbi.nlm.nih.gov/18056558/

Disclaimer: Statements made have not been evaluated by the TGA (Australian Therapeutic Goods Administration) or FDA (U.S. Food & Drug Administration). Products sold are not intended to diagnose, treat, cure, or prevent any disease. Manuka honey is not intended to be a substitute for other medicines or advice and is best used in conjunction with any existing treatment plans. Please consult your healthcare professional before beginning any treatment. For all of the science-backed and evidence-based information on the natural healing properties of medicinal-grade Manuka honey, please refer to the latest published Manuka Honey research and use at your own discretion.