Honey has been revered for its natural healing benefits in many ancient cultures for centuries and the science is starting to catch up.
Several clinical trials have recently been published on the proven healing properties and medicinal benefits of antibacterial Manuka honey.
We have linked to a number of respectable science journals citing these science-backed, evidence-based, and peer-reviewed research papers for reference below.
Antiviral and Immunomodulatory Effects of Phytochemicals from Honey against COVID-19:
Authors: Mohammad A. I. Al-Hatamleh, Ma’mon M. Hatmal, Kamran Sattar, Suhana Ahmad, Mohd Zulkifli Mustafa, Marcelo De Carvalho Bittencourt, and Rohimah Mohamud
Published: 29 October, 2020
Link: Antiviral and Immunomodulatory Effects of Phytochemicals from Honey against COVID-19: Potential Mechanisms of Action and Future Directions
Anti-influenza viral effects of honey in vitro: potent high activity of manuka honey:
Author:
Published: 29 May, 2014
Link: Anti-influenza viral effects of honey in vitro: potent high activity of manuka honey
In vitro antiviral activity of honey against VZV: A medicine study for potential remedy for shingles:
Therapeutic Manuka Honey:
Authors: Dee A. Carter,,* Shona E. Blair, Nural N. Cokcetin, Daniel Bouzo, Peter Brooks, Ralf Schothauer, and Elizabeth J. Harry
Published: 20 Apr, 2016
Link: Therapeutic Manuka Honey: No Longer So Alternative
Antibacterial effect of Manuka honey on Clostridium difficile:
Author: Eric N Hammond and Eric S Donkor
Published: 7 May, 2013
Link: Antibacterial effect of Manuka honey on Clostridium difficile
Killing of Six Common Wound Pathogens With Manuka Honey Dressings:
Author: Published: 28 June, 2017
Link: Comprehensive In Situ Killing of Six Common Wound Pathogens With Manuka Honey Dressings Using a Modified AATCC-TM100
The unusual antibacterial activity of medical-grade Leptospermum honey:
Author: Published: 10 June, 2009
Link: The unusual antibacterial activity of medical-grade Leptospermum honey: antibacterial spectrum, resistance and transcriptome analysis
Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains:
Author: Jing Lu, Lynne Turnbull, Catherine M. Burke, Michael Liu, Dee A. Carter, Ralf C. Schlothauer, Cynthia B. Whitchurch, and Elizabeth J. HarryPublished: 25 Mar, 2014
Link: Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains with different biofilm-forming abilities
Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka:
Secondary Bacterial Infections Associated with Influenza Pandemics:
Author: Denise E. Morris, David W. Cleary, and Stuart C.Clarke Published: 23 June, 2017
Link: Secondary Bacterial Infections Associated with Influenza Pandemics
Effect of Honey, Dextromethorphan, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents:
Authors: Ian M. Paul, MD, MSc; Jessica Beiler, MPH; Amyee McMonagle, RNPublished: December, 2007
Link: Effect of Honey, Dextromethorphan, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents
Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections:
Author: Victoria C. Nolan, James Harrison, John E. E. Wright, Jonathan A. G. CoxPublished: 31 October, 2020
Link: Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections: A Systematic Review
Protective effects of Manuka honey:
Authors:
Published: 2 August, 2018
Link: Protective effects of Manuka honey on LPS-treated RAW 264.7 macrophages.
Part 2: Control of oxidative stress induced damage, increase of antioxidant enzyme activities and attenuation of inflammation
Manuka honey attenuates oxidative damage:
Authors:
Published: 12 May, 2018
Link: Manuka honey attenuates oxidative damage induced by H2O2 in human whole blood in vitro
Manuka honey protects middle-aged rats from oxidative damage:
Author:
Published: November, 2013
Link: Manuka honey protects middle-aged rats from oxidative damage
Intravenous Administration of Manuka Honey Inhibits Tumor Growth and Improves Host Survival When Combined with Chemotherapy:
Authors: Maria J. Fernandez-Cabezudo, Rkia El-Kharrag, Fawaz Torab, Ghada Bashir, Junu A. George, Hakam El-Taji, Basel K. al-Ramadi
Published: 7 February, 2013
Link: Intravenous Administration of Manuka Honey Inhibits Tumor Growth and Improves Host Survival When Used in Combination with Chemotherapy in a Melanoma Mouse Model
Manuka honey synergistically enhances the chemopreventive effect on human colon cancer cells:
Effectiveness of honey on radiation-induced oral mucositis among patients with head and neck malignancies:
Oxidative stress, inflammation, and cancer: how are they linked?:
Author:
Published: 16 September, 2010
Link: Oxidative stress, inflammation, and cancer: how are they linked?
Inhibition of STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey:
Author: Priyanka Aryappalli, Khadija Shabbiri, Razan J. Masad, Roadha H. Al-Marri, Shoja M. Haneefa, Yassir A. Mohamed, Kholoud Arafat, Samir Attoub, Otavio Cabral-Marques, Khalil B. Ramadi, Maria J. Fernandez-Cabezudo, and Basel K. al-Ramadi
Published: 5 September, 2019
Link: Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor
Signaling Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer Cells:
Authors: Priyanka Aryappalli, Sarah S. Al-Qubaisi, Samir Attoub, Junu A. George, Kholoud Arafat, Khalil B. Ramadi, Yassir A. Mohamed, Mezoon M. Al-Dhaheri, Ashraf Al-Sbiei, Maria J. Fernandez-Cabezudo, and Basel K. al-Ramadi
Published: 14 August, 2017
Link: The IL-6/STAT3 Signaling Pathway Is an Early Target of Manuka Honey-Induced Suppression of Human Breast Cancer Cells
Manuka honey in the treatment of cystic fibrosis-associated chronic rhinosinusitis:
Authors:
Published: 2 October, 2020
Link: Manuka honey versus saline sinus irrigation in the treatment of cystic fibrosis-associated chronic rhinosinusitis: A randomised pilot trial
Mānuka honey-derived methylglyoxal enhances microbial sensing by T cells:
Authors:
Published: 2020
Link: Mānuka honey-derived methylglyoxal enhances microbial sensing by mucosal-associated invariant T cells
Molecular Mechanisms of Natural Honey Against H. pylori Infection:
The susceptibility of gastrointestinal pathogens to the antibacterial effect of manuka honey:
Author:
Published: 17 December, 2010
Link: The controlled in vitro susceptibility of gastrointestinal pathogens to the antibacterial effect of manuka honey
Effect of Manuka honey on the clinical levels of dental plaque:
Authors: Prathibha A. Nayak, Ullal A. Nayak, and R. Mythili
Published: December, 2010
Link: Effect of Manuka honey, chlorhexidine gluconate and xylitol on the clinical levels of dental plaque
Antibacterial potential of Manuka honey against three oral bacteria:
Author: Patrick R Schmidlin, Helen English, Warwick J Duncan, Georgios N. Balibasakis
Published: September, 2014
Link: Antibacterial potential of Manuka honey against three oral bacteria in vitro
The effects of manuka honey on plaque and gingivitis: a pilot study:
Author:
Published: April, 2004
Link: The effects of manuka honey on plaque and gingivitis: a pilot study
Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial:
Authors:
Published: 9 December, 2016
Link: Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial
The association of Leptospermum honey with cytokine expression of chronic rhinosinusitis patients:
Author:
Published: March, 2019
Link: The association of Leptospermum honey with cytokine expression in the sinonasal epithelium of chronic rhinosinusitis patients
Acceptability to patients of a honey dressing for non-healing venous leg ulcers:
Authors:
Published: May, 2004
Link: Acceptability to patients of a honey dressing for non-healing venous leg ulcers
Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies:
Author:
Published: 30 March, 2017
Link: Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies
Resolution of folliculitis decalvans with medical honey:
Author: Yeh, Jennifer E, Hartman, Rebecca I, Xu, Jia, Hoang, Mai, Yasuda, Mariko R
Published: August, 2019
Link: Resolution of folliculitis decalvans with medical honey
Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers:
Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration:
Author:
Published: 2017
Link: Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration
Premium medicinal Manuka honey is defined as high-grade MGO Manuka honey that is scientifically tested for its curative compounds such as flavonoids, phenolic acids and dicarbonal compounds.
This honey presents higher levels of MGO (Methylglyoxal) when compared to table-grade Manuka honey and is naturally bio-active with anti-bacterial, antimicrobial, antiseptic, and anti-inflammatory properties for the holistic prevention and treatment of various health ailments.
Commonly known uses include: burns, wounds, infections, oral care, ulcers, gut health, colds & flu, sore throats, coughs, skincare, immunity building, and greater health and wellbeing.
The higher the MGO number of the Manuka Honey, the stronger its antimicrobial bioactivity levels and the more potent the natural medicinal benefits.
At Biosota Organics, our passion lies in the natural healing power of Manuka honey. Our Manuka honey is cultivated with science, love and generations of beekeeping experience.
The MGO levels of Biosota’s high strength medicinal Manuka honey ranges are regularly tested and verified authentic by independent accredited laboratories in Australia and New Zealand.
Download our fact sheets below to learn more about the clinically proven benefits of medicinal Manuka honey.